User Manual


































BIOFIT™ Features and Benefits High-Strength 2-Octyl Cyanoacrylate Formulation Octyl-cyanoacrylate has the greatest clinical tensile strength among available tissue Glues and a broader indication for clinical use. Microbial Barrier and Waterproof ProtectionBIOFIT™ Glue protects patients by preventing bacteria and water from reaching the wound, reducing the chance of infection and allowing patients to shower immediately following surgery.


Precision Applicator BIOFIT™’s patented applicator is designed to provide greater coverage with less Glue material and requires no catalyst to activate its Glue properties. This self-contained applicator increases efficiency in the OR, can be used on multiple lacerations, and reduces waste.


Optimum ViscosityThe formula neither runs nor clogs, resulting in the right balance of effectiveness and efficiency every time. Increased Patient ComfortBIOFIT™ Glue reduces not only physical pain, but also the anxiety associated with needles used for anesthetic administration—especially for children.


BIOFIT™ Glue also reduces the risk of needle stick injury for physicians and patients. Speed of ApplicationThe application and setting of BIOFIT™ Glue is at least three times faster than wound closure with sutures. In less than three minutes, BIOFIT™ Glue provides the strength of approximated healed tissue at seven days. No Need For Suture RemovalBIOFIT™ Glue sloughs off the skin during the wound healing period (usually five to 10 days).


Although physicians may want to check a healed wound after this time has elapsed, a follow-up visit for suture or staple removal is not required. Ease Of UseThe finesse required to apply BIOFIT™ Glue is more easily and quickly learned than that for suturing. Although proper use of BIOFIT™ is an easily acquired skill, physicians and licensed medical practitioners should be trained in its use to ensure optimal results.


Cost-EffectivenessBIOFIT™ Glue reduces the need for suture kits, wound dressings, anesthetic injections, syringes, and other instruments. In addition, the speed of BIOFIT™ Glue application and the elimination of a follow-up physician visit for suture removal can reduce overall treatment costs.


BIOFIT™ has superior clinical characteristics, yet is priced to provide broad accessibility addressing modern healthcare’s need for cost containment. Technical Data SheetIntuitive can manufacture OCA and 2-OCA at own technology.Octyl cyanoacrylate (OCA), a cyanoacrylate ester, is an octyl ester of 2-cyano-2-propenoic acid. It is a clear colorless liquid with a sharp, irritating odor. Its chief use is as the main component of medical cyanoacrylate glues.


It can be encountered under various trade name including LiquiBand, BIOFIT™, FloraSeal, Dermabond, Nexaband, and others.In medical and veterinary applications, the related compounds n-butyl cyanoacrylate and isobutyl cyanoacrylate are commonly used. They are bacteriostatic and their use is usually painless. Butyl esters provide a stronger bond, but the glue is rigid. The octyl ester, while providing weaker bond, is more flexible.It polymerizes rapidly in presence of moisture.Heating to higher temperatures causes pyrolysis and depolymerization of thecured glue, producing gaseous products strongly irritant to lungs and eyes